Everything You Need to Know About Lyme Disease: Overview, Causes, Types, Stages, Symptoms, Diagnosis and Treatment

In stage 3 Lyme disease, we would find these signs and symptoms:

• Acrodermatitis Chronica atrophicans: This is the worst skin consequence of Lyme disease, and it is more common in European patients. Patients initially get a reddish rash and swelling in a tender area of the skin. Then, the skin starts to change, destroying the sweat gland, hair follicles, and its normal fibers. Sometimes the skin ulcerates, too.
• Lyme arthritis: This is the late-stage manifestation of Lyme disease in the joints. The patient reports significant pain in larger joints, usually the knee. It is more severe than the usual arthralgia found in stage 2 Lyme disease.
• Late neurologic abnormalities: In stage 3, the disease causes chronic progressive encephalomyelitis and other anomalies that feature radicular pain and symptoms similar to fibromyalgia. The array of signs and symptoms is significantly large, including cognitive impairment, seizures, hearing loss, and much more.