Everything You Need to Know About Lyme Disease: Overview, Causes, Types, Stages, Symptoms, Diagnosis and Treatment

In stage 2 Lyme disease, these symptoms are more common:

Fever
  • Malaise and fever: In this stage, the immune response starts to defend the body against the disease, and the body increases its temperature.
  • Musculoskeletal symptoms: They are probably the most common symptoms. Patients feel joint pain and stiffness. It is usually a monoarticular joint problem in the ankle, knee, or wrist joint
  • Neurologic symptoms: They are also common and include neuropathies of the cranial nerves causing facial nerve palsy. In other patients, it may trigger encephalopathy and meningitis. Headache is also prevalent, especially after the meningeal tissue is involved, and the most common signs of encephalopathy are confusion, changes in personality, and memory problems.
  • Skin symptoms: After erythema migrans, patients may also develop smaller macular rashes of 1 to 5 cm. We can find a bluish to red swelling located on the nipple’s areola or the ear’s lobe in some patients.