The skeleton makes up the most compact tissue in the body. However, contrary to what many people think, it is still a tissue, and it is composed of cells, just like the rest of the organism.
Your bones make up the body’s primary framework, but most of them are hollow or have a porous structure on the inside. The outside is very hard, and it is known as cortical bone. It is covered by a fibrous layer known as the periosteum. The interior is more fragile, and it is known as trabecular bone. It contains a cavity where the bone marrow is located.
Another structure attached to the bone is the cartilage. It is a bone-like tissue with a soft surface that usually serves as a cushion in our joints.
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If we take the bone to the microscope, we will see two different cells. Osteoblasts are bone-creating cells and form new layers of fresh bone. Osteoclasts have potent enzymes to destroy old bone tissue that needs to be renewed. So, your bones are very active, and these cells are supported by many others every day. Bone cancer can develop in any of these cells.
Overview
Bone cancer is not the most common malignant disease. It is actually very rare, and most cases of malignancy in the bone are due to bone metastasis, not bone cancer. The difference is that bone cancer starts in the bone. Bone metastasis begins elsewhere and spreads to the bone.
In adults, bone cancer is quite rare. Only 0.2% of cancers are actually bone cancers. It is called sarcoma, which is the name given to any cancer that develops in the connective tissue (the bones, the fatty tissue, the blood vessels, and other soft or fibrous tissues).