In all types of cancer, we can find weight loss as a predominant symptom, especially in advanced stages of cancer. Weight loss is the result of an increase in energy consumption by the tumour, a deficit of nutrients, loss of appetite, and aberrant inflammatory signalling between the tumour and the brain. There is muscle wasting, weakness, fatigue, and a severe impact on the quality of life.
Unintentional weight loss should be differentiated from other causes as in changes in the dietary pattern, an increase in physical exercise and other sources of energy consumption. Losing 5% of your weight in 6 months or less without any of these factors should raise an alarm and make you visit your doctor to find out the reason why.