8. Fever and night sweats
Fever and night sweats are rare symptoms associated with bone cancer and usually happen when tumor cells build up in the bone tissue and start to call up inflammatory cytokines. This build-up of tumor cells releases enzymes and proteins that trigger an immune response and produce certain hormones that can raise the body’s temperature. This is why people with bone cancer often experience fever and night sweats.
In some cases, the fever may be accompanied by chills and can be accompanied by other symptoms like nausea and vomiting. The intensity and frequency of the fever and night sweats vary depending on the size and location of the affected bone. In some cases, the fever and night sweats may be mild and go away with treatment.