This particular symptom is one of the most common, but it is found in many other health problems as well. Recurrent pain paired with other symptoms of this list should be checked out if you’re in doubt. Mild headaches are usually easy to calm, and the source should be identifiable. The ones due to brain tumors are often very intense and different from normal headaches. They appear shortly after waking up, and painkillers or common medications will do almost nothing against them. These can be intensified by coughing, screaming, or by strenuous physical activity. The headaches can change depending on the area the tumor is located.