19. Edema in the lower limbs
This is also a consequence of prostate cancer metastasis and advanced prostate cancer. In this case, the prostate gland is very large, compromising the venous or lymphatic return to the heart. When this happens, liquid tends to accumulate in lower areas, and the patient starts to experience swelling and edema. Cancer can also take the adjacent lymph nodes and causes a similar obstruction of the lymphatic or venous return.