16. Anemia
This is a symptom of advanced prostate cancer because localized cancer does not typically change the hemoglobin levels. There are many causes, including androgen deprivation, a nutritional problem, an infiltration of the bone marrow, treatment toxicity, or it can be a result of chronic inflammation. Androgen deprivation and treatment toxicity are causes of anemia in patients with ongoing treatment of prostate cancer. They are side effects of the treatment. Infiltration of the bone marrow is a problem that arises in the case of metastasis in large bones and impairs the production of red blood cells. And chronic inflammation is also a problem caused by prostate cancer, more likely in advanced disease.