Skin changes
They are more common as cancer grows. It can be a thickening of the skin, swelling, and redness, or skin dimpling. They result from a localized inflammation of the tissues and the creation of adherences to the skin.
Nipple abnormalities
It is usually a recent inversion of the nipple due to adherences of cancer to the skin. In other cases, we can find a spontaneous discharge of blood or ulceration of the nipple.